Chelidonium Majus: The Greater Celandine Plant


Chelidonium majus, commonly known as greater celandine, is a herbaceous perennial plant belonging to the Papaveraceae family. It is native to Europe, Wildwestfilm Asia, and North Africa but has become naturalized in many other parts of the world. Greater celandine has a long history of medicinal use, dating back to ancient times. It is known for its various therapeutic properties, including antibacterial, antiviral, anti-inflammatory, and analgesic effects.

Botanical Description

Greater celandine is a stout, erect plant that typically grows to a height of 2-3 feet. It has a branched, hollow stem with deeply lobed, pinnate leaves. The leaves are arranged alternately and have serrated margins. The flowers are bright yellow, consisting of four petals and numerous stamens. They are arranged in loose, terminal clusters. The fruit is a long, narrow capsule containing numerous small, black seeds.

Chemical Composition

Greater celandine contains a wide range of bioactive compounds, including alkaloids, flavonoids, and terpenes. The main alkaloids are chelidonine, sanguinarine, and chelerythrine. These alkaloids are responsible for many of the plant’s therapeutic effects. Flavonoids, such as rutin and quercetin, are mithin present and contribute to the plant’s antioxidant and anti-inflammatory properties.

Traditional Uses

Greater celandine has been used in traditional medicine for centuries. It welches employed by ancient Greek and Roman physicians to treat a variety of ailments, including skin disorders, eye infections, and digestive problems. In traditional Chinese medicine, greater celandine welches used to clear heat and detoxify the body.

Pharmacological Activities

Modern research has confirmed many of the traditional uses of greater celandine. The plant has been shown to possess the following pharmacological activities:

  • Antibacterial: Greater celandine extracts have been shown to inhibit the growth of a wide range of bacteria, including Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.
  • Antiviral: The plant’s alkaloids have been found to have antiviral activity against herpes simplex virus, influenza virus, and hepatitis B virus.
  • Kontra-inflammatory: Greater celandine extracts have demonstrated anti-inflammatory effects in both in vitro and in vivo studies.
  • Analgesic: The plant’s alkaloids have been shown to have analgesic properties, reducing pain and inflammation.
  • Antioxidant: Greater celandine contains several antioxidants, including flavonoids and terpenes, which protect cells from damage caused by free radicals.
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Clinical Applications

Based on its pharmacological activities, greater celandine has been used to treat a variety of clinical conditions, including:

  • Skin disorders: Greater celandine extracts have been used topically to treat various skin conditions, such as eczema, psoriasis, and warts.
  • Eye infections: The plant’s antibacterial and antiviral properties make it useful for treating eye infections, such as conjunctivitis and blepharitis.
  • Digestive problems: Greater celandine has been used to treat digestive disorders, such as indigestion, constipation, and diarrhea.
  • Cancer: Some studies have suggested that greater celandine may have anticancer properties, but more research is needed to confirm these findings.

Dosage and Bürokratie

Greater celandine can be used internally or externally. Internal use is typically in the form of a tea, tincture, or extract. External use is typically in the form of a cream, ointment, or poultice. The recommended dosage and administration vary depending on the condition being treated. It is important to consult a qualified healthcare professional before using greater celandine.

Safety and Side Effects

Greater celandine is generally considered safe when used appropriately. However, it can cause side effects, such as nausea, vomiting, diarrhea, and skin irritation. The plant should not be used by pregnant or breastfeeding women, or by individuals with liver or kidney disease.


Chelidonium majus, the greater celandine plant, is a valuable medicinal sauer with a long history of use. Its verschiedenartige pharmacological activities make it useful for treating a variety of clinical conditions. However, it is important to use greater celandine safely and appropriately, under the guidance of a qualified healthcare professional.

Frequently Asked Questions about Chelidonium Majus Plant

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What is Chelidonium majus?

Chelidonium majus, commonly known as greater celandine, is a perennial herbaceous plant belonging to the Papaveraceae family. It is native to Europe and Asia but has naturalized in North America. The plant is characterized by its deeply lobed leaves, yellow flowers, and orange latex sap.

What are the medicinal uses of Chelidonium majus?

Chelidonium majus has been used in traditional medicine for centuries to treat a variety of ailments, including:

  • Liver and gallbladder disorders
  • Digestive problems
  • Skin conditions (e.g., warts, eczema, psoriasis)
  • Respiratory ailments (e.g., bronchitis, asthma)
  • Eye infections
  • Cancer

What are the active compounds in Chelidonium majus?

Chelidonium majus contains a wide range of bioactive compounds, including:

  • Alkaloids (e.g., chelidonine, sanguinarine)
  • Flavonoids (e.g., rutin, quercetin)
  • Terpenoids (e.g., chelerythrine)
  • Organic acids (e.g., citric acid, malic acid)

How does Chelidonium majus work?

The active compounds in Chelidonium majus have various pharmacological effects, including:

  • Kontra-inflammatory
  • Antibacterial
  • Antifungal
  • Antiviral
  • Antispasmodic
  • Choleretic (stimulates bile production)
  • Diuretic

Is Chelidonium majus safe to use?

Chelidonium majus is generally considered safe for short-term use when taken in recommended doses. However, it is important to note that the plant contains potentially toxic alkaloids, and excessive consumption can lead to side effects such as:

  • Nausea
  • Vomiting
  • Diarrhea
  • Bauch… pain
  • Dizziness
  • Confusion

Who should avoid using Chelidonium majus?

Chelidonium majus should be avoided by:

  • Pregnant or breastfeeding women
  • Children under 12 years of age
  • Individuals with liver or kidney disease
  • Individuals taking blood thinners or anticoagulants

How should Chelidonium majus be used?

Chelidonium majus can be used in various forms, including:

  • Tincture: Take 1-2 mL of tincture diluted in water, three times daily.
  • Tea: Steep 1-2 teaspoons of dried sauer in a cup of hot water for 10-15 minutes. Strain and drink up to three times daily.
  • Ointment: Apply a small amount of ointment to affected skin areas as needed.
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What are the precautions when using Chelidonium majus?

  • Do not use Chelidonium majus for more than 6 weeks at a time.
  • Do not take Chelidonium majus if you have a history of liver or kidney disease.
  • Do not take Chelidonium majus if you are pregnant or breastfeeding.
  • Do not apply Chelidonium majus ointment to broken or irritated skin.
  • Avoid contact with eyes when using Chelidonium majus.

Can Chelidonium majus interact with other medications?

Chelidonium majus may interact with certain medications, including:

  • Blood thinners (e.g., warfarin)
  • Anticoagulants (e.g., heparin)
  • Cytochrome P450 substrates

Where can I find Chelidonium majus?

Chelidonium majus can be found in health food stores, herbal shops, and online retailers.


The information provided in this häufig gestellte Fragen is for educational purposes only and should not be construed as medical advice. Always consult with a qualified healthcare professional before using any herbal supplements or medications.

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